ABEmax mRNA (unmodified)
ABEmax mRNA encodes the ABEmax (Adenine Base Editor) protein, a second-generation genome-editing tool for precise adenine-to-guanine (A-to-G) conversions in DNA. Delivered as mRNA, it ensures rapid, high transient expression proportional to mRNA quantity without requiring nuclear uptake. Extensively characterized for its targeting window and off-target effects, ABEmax is ideal for research in gene function, genetic diseases, and therapeutic development.
Croyez’s ABEmax mRNA is generated through in vitro transcription, with a Cap1-modified 5' end and a poly(A) tail at the 3' end to mimic mature mRNAs. These optimizations enhance stability and performance, ensuring the mRNAs function like natural mature mRNAs in cells.
Croyez’s ABEmax mRNA is generated through in vitro transcription, with a Cap1-modified 5' end and a poly(A) tail at the 3' end to mimic mature mRNAs. These optimizations enhance stability and performance, ensuring the mRNAs function like natural mature mRNAs in cells.
| mRNA Length | 5962 nt |
| Base Composition | Unmodified bases |
| Concentration | 1.0 mg/ mL |
| Cap Modification | Cap 1 structure |
| Poly A Tail | Yes |
| Form | Liquid |
| Buffer | 1 mM sodium citrate buffer, pH 6.4. |
| Storage | Products can be stored at -80°C or below. We recommend to aliquot the mRNA solution for a better storage. Avoid repeated freeze/thaw cycles. |
| Shipping | The products are shipped on dry ice and should be avoided for freeze-thaw cycles. |
| Application | Gene function research, genetic disease studies, therapeutic development, genetic modification. |
| Shipping Conditions | Dry ice |
⮕ ABEmax mRNA (m1ψ substitution)
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Figure 2.
ABEmax mRNA (unmodified) was analyzed on a 1% TAE agarose gel at 100 V for 30 minutes.
Lane 1: Marker, RNA ladder (cat no: CR00004).
Lane 2: ABEmax mRNA (unmodified)
